Treatment of migraine related vertigo with Lamotrigine

[adam]

Treatment of migraine related vertigo with Lamotrigine
an observational study

Alexandre R. Bisdorff

"Migraine is a common cause of vertigo. The vertigo symptoms often occur independently of the headaches and have very variable duration and phenomenology. Treatment usually consists in giving prophylactic anti-migraineous medication. The anti-epileptic drug Lamotrigine (LTG) has been reported to be effective in treating migraine auras, isolated auras and to some extend migraine headaches. In this retrospective observational study, 19 patients, 6 male and 13 female, aged 52.3 years (range 28-84) treated with LTG and suffering from migraine and migraine related vertigo were evaluated. After a titration phase of 4 weeks patients took 100 mg of Lamotrigine per day in a single dose and were followed up for 3-4 months. The average vertigo frequency per month was significantly reduced from 18.1 to 5.4, the average headache frequency per month was reduced from 8.7 to 4.4 without reaching statistical significance. Lamotrigine at a daily dose of 100 mg seems to be effective in the treatment of migraine related vertigo. The effect on vertigo was more marked than on headaches."

http://www.mvertigo.org/articles/Treatm ... rigine.pdf

[hashithang]

I got a seriously life threatening rash/burn all over my body caused by taking Lamotrigine, i had a reaction to it called Steven Johnson's Syndrome, it was a serious rash that appears all over your body and burns you. I was warned of the risk before i took Lamotrigine,that i had a 1 in 10,000 chance of getting SJS but I got Steven's Johnson Syndrome anyway , even though it sounded like a small risk. If anyone takes lamotigrine and gets a rash, seek medical treatment.

[adam]

Good post; definitely any rash after starting a drug needs to be evaluated.

I have seen a family member with drug-induced SJS and it was a pretty horrific.

[susanne32570]

My sister and I also took Lamotrigine for Migraine with aura and both developed a rash. Were advised to stop taking immediately. Our rash went away within a week.